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Directed ortho,ortho'-dimetalation of hydrobenzoin: Rapid access to hydrobenzoin derivatives useful for asymmetric synthesis

A variety of ortho,ortho'-disubstituted hydrobenzoin derivatives are readily accessible through a directed ortho,ortho'-dimetalation strategy in which the alcohol functions in hydrobenzoin are deprotonated by n-BuLi and the resulting lithium benzyl alkoxides serve as directed metalation groups. The...

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Autores principales: Inhee Cho, Labros Meimetis, Lee Belding, Michael J. Katz, Travis Dudding, Robert Britton
Formato: Artigo
Lenguaje:Inglês
Publicado: Beilstein-Institut 2011-09-01
Colección:Beilstein Journal of Organic Chemistry
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Acceso en línea:https://doi.org/10.3762/bjoc.7.154
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