Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex

The mutant Chinese hamster ovary cell line MT58 contains a thermosensitive mutation in CTP:phosphocholine cytidylyltransferase, the regulatory enzyme in the CDP-choline pathway. As a result, MT58 cells have a 50% decrease in their phosphatidylcholine (PC) level within 24 h when cultured at the nonpe...

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Bibliografische gegevens

Hoofdauteurs:	Nicole Testerink, Michiel H.M. van der Sanden, Martin Houweling, J. Bernd Helms, Arie B. Vaandrager
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2009-11-01
Reeks:	Journal of Lipid Research
Onderwerpen:	CTP:phosphocholine cytidylyltransferase lipid droplets protein transport diacylglycerol
Online toegang:	http://www.sciencedirect.com/science/article/pii/S0022227520306842
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