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Metformin in polycystic ovary syndrome: unraveling multi-stage therapeutic mechanisms from puberty to long-term health outcomes

Polycystic ovary syndrome (PCOS) represents a prevalent endocrine disorder affecting reproductive-aged women worldwide, characterized by a variety of reproductive, metabolic, and psychological manifestations. This condition disrupts menstrual cycles and fertility, and significantly compromises quali...

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Principais autores: Weiwei Zeng, Yuning Luo, Juanfeng Ou, Dali Gan, Min Huang, Brian Tomlinson, Yiming Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-08-01
coleção:Frontiers in Pharmacology
Assuntos:
metformin
polycystic ovary syndrome
infertility
mechanism
drug therapy
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2025.1654372/full
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