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BLM Deficiency Is Not Associated with Sensitivity to Hydroxyurea-Induced Replication Stress

Bloom's syndrome (BS) displays one of the strongest known correlations between chromosomal instability and a high risk of cancer at an early age. BS cells combine a reduced average fork velocity with constitutive endogenous replication stress. However, the response of BS cells to replication stress...

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Autori principali: Kenza Lahkim Bennani-Belhaj, Géraldine Buhagiar-Labarchède, Nada Jmari, Rosine Onclercq-Delic, Mounira Amor-Guéret
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2010-01-01
Serie:Journal of Nucleic Acids
Accesso online:http://dx.doi.org/10.4061/2010/319754
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