PPP1R2 stimulates protein phosphatase-1 through stabilisation of dynamic subunit interactions
Abstract Protein Ser/Thr phosphatase PP1 is always associated with one or two regulatory subunits or RIPPOs. One of the earliest evolved RIPPOs is PPP1R2, also known as Inhibitor-2. Since its discovery nearly 5 decades ago, PPP1R2 has been variously described as an inhibitor, activator or (metal) ch...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2024-11-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-024-54256-4 |
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