Gefitinib facilitates PINK1/Parkin-mediated mitophagy by enhancing mitochondrial recruitment of OPTN
Gefitinib, a well-known epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor for the targeted therapy of lung cancer, induces autophagy in association with drug resistance. However, it remains unclear whether gefitinib treatment can affect the selective form of autophagy (i.e., mitophag...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
KeAi Communications Co. Ltd.
2022-09-01
|
| Collection: | Fundamental Research |
| Sujets: | |
| Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S2667325822001169 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|