Fiber-2, not Fiber-1, is the principal protective immunogen of fowl adenovirus serotype 4: insights from a comparative efficacy study of chimeric virus-based inactivated vaccines

Fowl adenovirus serotype 4 (FAdV-4) uniquely encodes two fiber proteins (fiber-1 and fiber-2), while FAdV-8b possesses only one. Although our previous study showed that an inactivated vaccine based on a chimeric virus with FAdV-4′s fiber-1 replaced by FAdV-8b's fiber (rFAdV-4-Δfiber1-fiber/8b) confe...

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Autors principals:	Panpan Yang, Mengjia Xiang, Minghe Xu, Yutao Zhu, Luyao Qiu, Muran Xu, Bingjie Zhang, Yaru Zhang, Jin Qiu, Dongdong Yang, Qilong Qiao, Yanfang Cong, Baiyu Wang, Jianli Li, Jun Zhao
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-05-01
Col·lecció:	Poultry Science
Matèries:	Fowl adenovirus serotype 4 Fowl adenovirus serotype 8b Hepatitis-hydropericardium syndrome Inclusion body hepatitis Bivalent vaccine
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0032579126002610
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