Vascular endothelial cell expression of JAK2V617F is sufficient to promote a pro-thrombotic state due to increased P-selectin expression

Thrombosis is the main cause of morbidity and mortality in patients with JAK2V617F myeloproliferative neoplasms. Recent studies have reported the presence of JAK2V617F in endothelial cells of some patients with myeloproliferative neoplasms. We investigated the role of endothelial cells that express...

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Principais autores:	Alexandre Guy, Virginie Gourdou-Latyszenok, Nicolas Le Lay, Claire Peghaire, Badr Kilani, Juliana Vieira Dias, Cécile Duplaa, Marie-Ange Renault, Cécile Denis, Jean Luc Villeval, Yacine Boulaftali, Martine Jandrot-Perrus, Thierry Couffinhal, Chloe James
格式:	Artigo
語言:	Inglês
出版:	Ferrata Storti Foundation 2019-01-01
叢編:	Haematologica
在線閱讀:	https://haematologica.org/article/view/8743
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