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Identifying hub genes in response to ustekinumab and the impact of ustekinumab treatment on fibrosis in Crohn’s disease

IntroductionCrohn’s disease (CD) is a chronic inflammatory disease. Approximately 50% of patients with CD progressed from inflammation to fibrosis. Currently, there are no effective drugs for treating intestinal fibrosis. Biologic therapies for CD such as ustekinumab have benefited patients; however...

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Hlavní autoři: Ying Xu, Shu Wang, Ziping Ye, Hongjie Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-05-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1401733/full
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