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Identification of small molecules as novel anti-adipogenic compounds based on Connectivity Map

Several physiological and pathological conditions such as aging, obesity, diabetes, anorexia nervosa are associated with increased adipogenesis in the bone marrow. A lack of effective drugs hinder the improved treatment for aberrant accumulation of bone marrow adipocytes. Given the higher costs, lon...

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Principais autores: Shuang Zhang, Nicholas Lyons, Marijke Koedam, Jeroen van de Peppel, Johannes P.T.M. van Leeuwen, Bram C. J. van der Eerden
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-12-01
Colecção:Frontiers in Endocrinology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2022.1017832/full
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