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Loss, amplification or mistiming of the daily rhythms of metabolic markers in patients with cirrhosis

Background & Aims: The aim of the present study was to evaluate the temporal dynamics of metabolites in patients with cirrhosis using hourly plasma samples collected over a full 24-hour cycle in 17 outpatients with cirrhosis of varying severity (9 males, 58 [39-77] years, 12 compensated/5 decomp...

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Principais autores: Holly-May Lewis, Cheryl M. Isherwood, Ali R. Mani, Benita Middleton, Marsha Y. Morgan, Debra J. Skene, Sara Montagnese
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-03-01
coleção:JHEP Reports
Assuntos:
cirrhosis
metabolism
metabolomics
diurnal rhythms
circadian rhythms
liver clock
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589555925004033
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