Investigating the role of MAB_1915 in intrinsic resistance to multiple drugs in Mycobacterium abscessus

ABSTRACT The increasing clinical significance of Mycobacterium abscessus is owed to its innate high-level, broad-spectrum resistance to antibiotics and therefore rapidly evolves as an important human pathogen. This warrants the identification of novel targets for aiding the discovery of new drugs or...

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Hauptverfasser:	Buhari Yusuf, Shuai Wang, Md Shah Alam, Jingran Zhang, Zhiyong Liu, Ziwen Lu, Jie Ding, Gift Chiwala, Yamin Gao, Cuiting Fang, Shahzad Akbar Khan, Xirong Tian, Md Mahmudul Islam, H. M. Adnan Hameed, Dmitry A. Maslov, Nanshan Zhong, Jinxing Hu, Tianyu Zhang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2024-10-01
Schriftenreihe:	Microbiology Spectrum
Schlagworte:	Mycobacterium abscessus MAB_1915 fatty acid-CoA ligase cell envelope permeability intrinsic drug resistance
Online-Zugang:	https://journals.asm.org/doi/10.1128/spectrum.03974-23
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