A novel non-invasive murine model for rapidly testing drug activity via inhalation administration against Mycobacterium tuberculosis

The efficacy of many compounds against Mycobacterium tuberculosis is often limited when administered via conventional oral or injection routes due to suboptimal pharmacokinetic characteristics. Inhalation-based delivery methods have been investigated to achieve high local therapeutic doses in the lu...

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Ngā kaituhi matua:	Xirong Tian, Yamin Gao, Chunyu Li, Wanli Ma, Jingran Zhang, Yanan Ju, Jie Ding, Sanshan Zeng, H. M. Adnan Hameed, Htin Lin Aung, Nanshan Zhong, Gregory M. Cook, Jinxing Hu, Tianyu Zhang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Frontiers Media S.A. 2025-01-01
Rangatū:	Frontiers in Pharmacology
Ngā marau:	inhalation administration autoluminescence tuberculosis murine model chemotherapy
Urunga tuihono:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1400436/full
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!