Cryo-EM structure of the human histamine H1 receptor/Gq complex
Histamine receptors are effective targets for allergy treatments and antihistamines are the first choice of many allergic disorders, but the exact mechanism of agonist binding and receptor activation remain unknown. Here, the authors present the cryo-EM structure of histamine-bound H1R/Gq complex an...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2021-04-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-021-22427-2 |
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