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Label-Free Quantification of Bilirubin Using a Refractive Index-Insensitive Nanolaminate SERS Substrate

Bilirubin is an important biomarker, where a small unbound fraction dissociated from albumin can cross the blood–brain barrier and induce neurotoxicity, such as kernicterus, at low nanomolar levels. Accurate detection of this low-level fraction remains challenging. Surface-enhanced Raman spectroscop...

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Autors principals: Jiwon Yun, Inyoung Kim, Wonil Nam
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2026-05-01
Col·lecció:Biosensors
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Accés en línia:https://www.mdpi.com/2079-6374/16/5/282
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