TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions

Summary: Estrogen receptor-α (ER) drives tumor development in ER-positive (ER+) breast cancer. The transcription factor GATA3 has been closely linked to ER function, but its precise role in this setting remains unclear. Quantitative proteomics was used to assess changes to the ER complex in response...

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Bibliografische gegevens

Hoofdauteurs:	Rebecca Broome, Igor Chernukhin, Stacey Jamieson, Kamal Kishore, Evangelia K. Papachristou, Shi-Qing Mao, Carmen Gonzalez Tejedo, Areeb Mahtey, Vasiliki Theodorou, Arnoud J. Groen, Clive D’Santos, Shankar Balasubramanian, Anca Madalina Farcas, Rasmus Siersbæk, Jason S. Carroll
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2021-02-01
Reeks:	Cell Reports
Onderwerpen:	TET2 estrogen receptor GATA3 5hmC gene regulation enhancers
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2211124721000899
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