Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity

Allogeneic hematopoietic cell transplantation (Allo-HCT) is a curative therapy for hematological malignancies (i.e., leukemia and lymphoma) due to the graft-versus-leukemia (GVL) activity mediated by alloreactive T cells that can eliminate residual malignant cells and prevent relapse. However, the s...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Qingxiao Song, Ubaydah Nasri, Ryotaro Nakamura, Paul J. Martin, Defu Zeng
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2022-05-01
سلاسل:	Frontiers in Immunology
الموضوعات:	graft versus leukaemia (GVL) graft versus host disease (GVHD) naive T cell depletion PD-L1 chemokine and chemokine receptors anti-IL-2
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.907673/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!