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Parameters and determinants of responses to selection in antibody libraries.

The sequences of antibodies from a given repertoire are highly diverse at few sites located on the surface of a genome-encoded larger scaffold. The scaffold is often considered to play a lesser role than highly diverse, non-genome-encoded sites in controlling binding affinity and specificity. To gau...

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主要な著者: Steven Schulz, Sébastien Boyer, Matteo Smerlak, Simona Cocco, Rémi Monasson, Clément Nizak, Olivier Rivoire
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2021-03-01
シリーズ:PLoS Computational Biology
オンライン・アクセス:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008751&type=printable
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