A novel dual-color reporter for identifying insulin-producing beta-cells and classifying heterogeneity of insulinoma cell lines.

Many research studies use immortalized cell lines as surrogates for primary beta- cells. We describe the production and use of a novel "indirect" dual-fluorescent reporter system that leads to mutually exclusive expression of EGFP in insulin-producing (INS(+)) beta-cells or mCherry in non-beta-cells...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Nan Sook Lee, Joyce G Rohan, Madison Zitting, Sonia Kamath, Andrew Weitz, Arnold Sipos, Paul M Salvaterra, Kouichi Hasegawa, Martin Pera, Robert H Chow
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Public Library of Science (PLoS) 2012-01-01
Sarja:	PLoS ONE
Linkit:	http://europepmc.org/articles/PMC3329476?pdf=render
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