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Free Radical Production Induced by Nitroimidazole Compounds Lead to Cell Death in <i>Leishmania infantum</i> Amastigotes

<i>Leishmania infantum</i> is the vector-borne trypanosomatid parasite causing visceral leishmaniasis in the Mediterranean basin. This neglected tropical disease is treated with a limited number of obsolete drugs that are not exempt from adverse effects and whose overuse has promoted the emergence o...

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Principais autores: Julia Andrés-Rodríguez, María-Cristina González-Montero, Nerea García-Fernández, Estefanía Calvo-Álvarez, María-Yolanda Pérez-Pertejo, Rosa-María Reguera-Torres, Rafael Balaña-Fouce, Carlos García-Estrada
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-08-01
Serier:Molecules
Fag:
<i>Leishmania infantum</i>
visceral leishmaniais
neglected tropical diseases
nitroaromatic compounds
drug repurposing
pretomanid
Online adgang:https://www.mdpi.com/1420-3049/29/17/4041
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