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Parallel Spinal Pathways for Transmitting Reflexive and Affective Dimensions of Nocifensive Behaviors Evoked by Selective Activation of the Mas-Related G Protein-Coupled Receptor D-Positive and Transient Receptor Potential Vanilloid 1-Positive Subsets of Nociceptors

The high incidence of treatment-resistant pain calls for the urgent preclinical translation of new analgesics. Understanding the behavioral readout of pain in animals is crucial for efficacy evaluation when developing novel analgesics. Mas-related G protein-coupled receptor D-positive (Mrgprd+) and...

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Bibliografiska uppgifter
Huvudupphov: Liang-Biao Wang, Xiao-Jing Su, Qiao-Feng Wu, Xiang Xu, Xin-Yue Wang, Mo Chen, Jia-Reng Ye, Abasi Maimaitiabula, Xiao-Qing Liu, Wen Sun, Yan Zhang
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2022-05-01
Serie:Frontiers in Cellular Neuroscience
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Länkar:https://www.frontiersin.org/articles/10.3389/fncel.2022.910670/full
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