Voltage-dependent gating in a "voltage sensor-less" ion channel.
The voltage sensitivity of voltage-gated cation channels is primarily attributed to conformational changes of a four transmembrane segment voltage-sensing domain, conserved across many levels of biological complexity. We have identified a remarkable point mutation that confers significant voltage de...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2010-02-01
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| Серии: | PLoS Biology |
| Online-ссылка: | https://doi.org/10.1371/journal.pbio.1000315 |
| Метки: |
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