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The kinetics of uracil-N-glycosylase distribution inside replication foci

Abstract Mismatched nucleobase uracil is commonly repaired through the base excision repair initiated by DNA uracil glycosylases. The data presented in this study strongly indicate that the nuclear uracil-N-glycosylase activity and nuclear protein content in human cell lines is highest in the S phas...

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Auteurs principaux: Anna Ligasová, Ivo Frydrych, Barbora Piskláková, David Friedecký, Karel Koberna
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-01-01
Collection:Scientific Reports
Accès en ligne:https://doi.org/10.1038/s41598-024-84408-x
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