Immune inhibitory function of bovine CTLA-4 and the effects of its blockade in IFN-γ production
Abstract Background Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is known as an immune inhibitory receptor that is expressed on activated effector T cells and regulatory T cells. When CTLA-4 binds to CD80 or CD86, immunoinhibitory signals are transmitted to retain a homeostasis of the immune response....
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2019-10-01
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| coleção: | BMC Veterinary Research |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12917-019-2082-7 |
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