Associations of six insulin resistance-related indices with the risk and progression of cardio-renal-metabolic multimorbidity: evidence from the UK biobank

Abstract Background Insulin resistance (IR)-related indices are increasingly recognized as important contributors to cardio-renal-metabolic (CRM) diseases. However, most prior studies have focused on isolated outcomes or cross-sectional disease status, lacking dynamic insight into disease progressio...

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Principais autores:	Lulu Liu, Guangzan Yu, Xuhou Ji, Yunlong Wang, Hua He
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-09-01
Series:	Cardiovascular Diabetology
Assuntos:	Insulin resistance Cardio-renal-metabolic multimorbidity Multi-state model Mediation UK biobank
Acceso en liña:	https://doi.org/10.1186/s12933-025-02928-w
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