Glioma angiogenesis is boosted by ELK3 activating the HIF-1 $$\alpha$$ α /VEGF-A signaling axis

Abstract Background Clinical studies have shown that first-line use of anti-angiogenetic therapy can prolong progression-free survival but little progress has been made in extending the overall survival of the patients. We explored the role of ELK3 in glioma angiogenesis to improve and design more e...

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Detalhes bibliográficos

Principais autores:	Mou Yueyang, Hu Yaqin, Xue Guolian, Zhao Wenjian, Jiao Yang, Li Chen, Cao Haiyan, Chao Min, Deng Jianping, Dai Penggao, Zhu Hongli, Wang Liang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-07-01
coleção:	BMC Cancer
Assuntos:	Glioma Angiogenesis ELK3 VEGF-A HIF-1 $$\alpha$$ α
Acesso em linha:	https://doi.org/10.1186/s12885-023-11069-w
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