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Discovery of ALA-hydroxypyridinone hybrids: novel strategies for photodynamic therapy against superficial tumours

Superficial tumours can be effectively treated with photodynamic therapy (PDT), which is characterised by its targeted approach and enhanced safety profile. 5-aminolevulinic acid (ALA), a precursor to the endogenous photosensitiser PpIX, has been widely utilised in PDT. However, its high hydrophilic...

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Autori principali: Xiaoying Jiang, Meiling Feng, Xiaotian Niu, Shan Wang, Yinyan Sun, Wenchao Chen, Renren Bai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2026-12-01
Serie:Journal of Enzyme Inhibition and Medicinal Chemistry
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Accesso online:https://www.tandfonline.com/doi/10.1080/14756366.2026.2700840
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