Chicken IRF10 suppresses the cGAS-STING-IFN antiviral signaling pathway by targeting IRF7

IntroductionThe innate immune cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING)-interferon (IFN) signaling axis is a cornerstone of antiviral innate immunity in chickens, with chicken interferon regulatory factor 7 (chIRF7) serving as the principal transcription factor downstream...

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Hlavní autoři:	Sen Jiang, Jingyu He, Kun Wang, Mengjia Lv, Hongjian Han, Bingjie Sun, Nanhua Chen, Wanglong Zheng, Jianzhong Zhu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2026-02-01
Edice:	Frontiers in Immunology
Témata:	antiviral signaling cGAS-STING chicken innate immunity IRF10
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1767491/full
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