Uncovering the genetic architecture and evolutionary roots of androgenetic alopecia in African men

Summary: Androgenetic alopecia is a highly heritable trait. However, much of our understanding about the genetics of male-pattern baldness comes from individuals of European descent. Here, we examined a dataset comprising 2,136 men from Ghana, Nigeria, Senegal, and South Africa that were genotyped u...

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Principais autores:	Rohini Janivara, Ujani Hazra, Aaron Pfennig, Maxine Harlemon, Michelle S. Kim, Muthukrishnan Eaaswarkhanth, Wenlong C. Chen, Adebola Ogunbiyi, Paidamoyo Kachambwa, Lindsay N. Petersen, Mohamed Jalloh, James E. Mensah, Andrew A. Adjei, Ben Adusei, Maureen Joffe, Serigne M. Gueye, Oseremen I. Aisuodionoe-Shadrach, Pedro W. Fernandez, Thomas E. Rohan, Caroline Andrews, Timothy R. Rebbeck, Akindele O. Adebiyi, Ilir Agalliu, Joseph Lachance
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2025-07-01
叢編:	HGG Advances
主題:	Africa evolutionary genetics generalizability GWAS male-pattern baldness polygenic scores
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2666247725000314
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