Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters

A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively charged trimethylammonium moiety ([H₂L^R]Cl, R = H, Me, Et, Ph) and four copper(II) complexes [Cu(HL^R)Cl]Cl (<b>1</b>–<b>4</b>) were synthesised with the aim to study (i) their antipro...

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Detalhes bibliográficos

Principais autores:	Miljan N. M. Milunović, Oleg Palamarciuc, Angela Sirbu, Sergiu Shova, Dan Dumitrescu, Dana Dvoranová, Peter Rapta, Tatsiana V. Petrasheuskaya, Eva A. Enyedy, Gabriella Spengler, Marija Ilic, Harald H. Sitte, Gert Lubec, Vladimir B. Arion
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-08-01
coleção:	Biomolecules
Assuntos:	thiosemicarbazones copper(II) complexes cytotoxicity organic cation transporters (OCT1–3) inhibitors
Acesso em linha:	https://www.mdpi.com/2218-273X/10/9/1213
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