Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior

Summary: The RASopathy neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant genetic disorders. In NF1 patients, neurological issues may result from damaged myelin, and mice with a neurofibromin gene (Nf1) mutation show white matter (WM) defects including myelin decompaction. U...

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Bibliografiske detaljer

Principais autores:	Alejandro López-Juárez, Haley E. Titus, Sadiq H. Silbak, Joshua W. Pressler, Tilat A. Rizvi, Madeleine Bogard, Michael R. Bennett, Georgianne Ciraolo, Michael T. Williams, Charles V. Vorhees, Nancy Ratner
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2017-04-01
Serier:	Cell Reports
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2211124717304503
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