Molecular Characterization of Circulating Tumor Cells Enriched by A Microfluidic Platform in Patients with Small-Cell Lung Cancer

At initial diagnosis, most patients with small-cell lung cancer (SCLC) present with metastatic disease with a high number of tumor cells (CTCs) circulating in the blood. We analyzed RNA transcripts specific for neuroendocrine and for epithelial cell lineages, and Notch pathway delta-like 3 ligand (<...

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Autori principali:	Eva Obermayr, Christiane Agreiter, Eva Schuster, Hannah Fabikan, Christoph Weinlinger, Katarina Baluchova, Gerhard Hamilton, Maximilian Hochmair, Robert Zeillinger
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2019-08-01
Serie:	Cells
Soggetti:	small-cell lung carcinoma circulating tumor cells microfluidics gene expression analysis synaptophysin chromogranin A rovalpituzumab tesirine
Accesso online:	https://www.mdpi.com/2073-4409/8/8/880
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