Osteoarthritis and depression a bidirectional TwoSample Mendelian randomization study on genetic causal association

Abstract Background Epidemiological observations suggest a potential causal relationship between osteoarthritis and depression. Alternatively, this association might arise from the simple co-occurrence of osteoarthritis and depression due to shared genetic or environmental risk factors within the po...

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Autori principali:	Haozhu Chen, Jinmei Tan, Kaiwei Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2026-05-01
Serie:	BMC Musculoskeletal Disorders
Soggetti:	Depression Osteoarthritis Mendelian Randomization Genome-Wide Association Study
Accesso online:	https://doi.org/10.1186/s12891-026-09872-0
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