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Gene co-expression network analysis identifies BRCC3 as a key regulator in osteogenic differentiation of osteoblasts through a β-catenin signaling dependent pathway

Objective(s): The prognosis of osteoporosis is very poor, and it is very important to identify a biomarker for prevention of osteoporosis. In this study, we aimed to identify candidate markers in osteoporosis and to investigate the role of candidate markers in osteogenic differentiation. Materials a...

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Main Authors: Lixiong Cai, Zhiqian Huo, Haiyun Yang, Fengchun He, Zhenglin Cao, Feng Wu, Lianjun Liu, Bingyin Sun
Format: Artigo
Language:Inglês
Published: Mashhad University of Medical Sciences 2019-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
BRCC3
β-catenin
Osteoblasts
Osteogenic differentiation
Osteoporosis
Online Access:http://ijbms.mums.ac.ir/article_12099_dfeb08fd6582e423228ec856870d5806.pdf
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