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Decrease in RNase HII and Accumulation of lncRNAs/DNA Hybrids: A Causal Implication in Psoriasis?

Functional long non-coding RNAs (lncRNAs) have been in the limelight in aging research because short telomeres are associated with higher levels of TERRA (Telomeric Repeat containing RNA). The genomic instability, which leads to short telomeres, is a mechanism observed in cell aging and in a class o...

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Principais autores: Ecmel Mehmetbeyoglu, Leila Kianmehr, Murat Borlu, Zeynep Yilmaz, Seyma Basar Kılıc, Hassan Rajabi-Maham, Serpil Taheri, Minoo Rassoulzadegan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-02-01
Serier:Biomolecules
Fag:
psoriasis
non-coding RNAs
telomere length
RNA–DNA hybrid
TERRA
RNase HII
Online adgang:https://www.mdpi.com/2218-273X/12/3/368
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