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Genetic modification of cystic fibrosis with ΔF508 mutation of CFTR gene using the CRISPR system in peripheral blood mononuclear cells

Objective(s): Cystic fibrosis (CF) is an inherited autosomal recessive disease that is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The present study aimed to investigate the genetic modification of CF with ΔF508 mutation of the CFTR gene using CRISPR i...

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Principais autores: Sepideh Khatibi, Mohammad Reza Modaresi, Reza Kazemi Oskuee, Mohammad Salehi, Hamid Aghaei
פורמט: Artigo
שפה:Inglês
יצא לאור: Mashhad University of Medical Sciences 2021-01-01
סדרה:Iranian Journal of Basic Medical Sciences
נושאים:
cftr gene
crispr
cystic fibrosis
peripheral blood mononuclear cells
δf508 mutation
גישה מקוונת:https://ijbms.mums.ac.ir/article_17031_41e69d647dcaba0322ebd32eea51c085.pdf
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