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Exceptional in vivo catabolism of neurodegeneration-related aggregates

Abstract Neurodegenerative diseases are linked to a systemic enzyme resistance of toxic aggregated molecules and their pathological consequences. This paper presents a unique phenomenon that Philodina acuticornis, a bdelloid rotifer, is able to catabolize different types of neurotoxic peptide and pr...

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Hlavní autoři: Zsolt Datki, Zita Olah, Tibor Hortobagyi, Lilla Macsai, Katalin Zsuga, Livia Fulop, Zsolt Bozso, Bence Galik, Eva Acs, Angela Foldi, Amanda Szarvas, Janos Kalman
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2018-01-01
Edice:Acta Neuropathologica Communications
Témata:
Alpha-synuclein
Bdelloid rotifer
Beta-amyloid
Catabolism
Lifespan
Prion
On-line přístup:http://link.springer.com/article/10.1186/s40478-018-0507-3
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