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In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA

Drug-resistant tuberculosis (TB) threatens global TB control and is a major public health concern in several countries. We therefore developed a multiplex assay (LINE-TB/MDR) that is able to identify the most frequent mutations related to rifampicin (RMP) and isoniazid (INH) resistance. The assay is...

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Principais autores: Sergio Luiz Montego Ferreira Junior, Elis Regina Dalla Costa, Paula Gonçalves dos Santos, Harrison Magdinier Gomes, Marcia Susana Nunes Silva, Leonardo Souza Esteves, Martha Maria Oliveira, Raquel de Abreu Maschmann, Afrânio Lineu Kritski, Philip Noel Suffys, Maria Lucia Rosa Rossetti
Format: Artigo
Sprog:Inglês
Udgivet: Fundação Oswaldo Cruz (FIOCRUZ) 2014-06-01
Serier:Memorias do Instituto Oswaldo Cruz
Fag:
Mycobacterium tuberculosis
resistance
hybridisation
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300307&lng=en&tlng=en
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