Antibody fragments functionalized with non-canonical amino acids preserving structure and functionality - A door opener for new biological and therapeutic applications

Functionalization of proteins by incorporating reactive non-canonical amino acids (ncAAs) has been widely applied for numerous biological and therapeutic applications. The requirement not to lose the intrinsic properties of these proteins is often underestimated and not considered. Main purpose of t...

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Principais autores:	Hana Hanaee-Ahvaz, Monika Cserjan-Puschmann, Florian Mayer, Christopher Tauer, Bernd Albrecht, Paul G. Furtmüller, Birgit Wiltschi, Rainer Hahn, Gerald Striedner
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2023-12-01
叢編:	Heliyon
主題:	E. coli Non-canonical amino acids Antigen binding fragment Micro-bioreactor cultivations
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2405844023096718
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