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Golgi tethering factor golgin-97 suppresses breast cancer cell invasiveness by modulating NF-κB activity

Abstract Background Golgin-97 is a tethering factor in the trans-Golgi network (TGN) and is crucial for vesicular trafficking and maintaining cell polarity. However, the significance of golgin-97 in human diseases such as cancer remains unclear. Methods We searched for a potential role of golgin-97...

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Main Authors: Rae-Mann Hsu, Cai-Yan Zhong, Chih-Liang Wang, Wei-Chao Liao, Chi Yang, Shih-Yu Lin, Jia-Wei Lin, Hsiao-Yun Cheng, Po-Yu Li, Chia-Jung Yu
Format: Artigo
Language:Inglês
Published: BMC 2018-04-01
Series:Cell Communication and Signaling
Subjects:
Golgin-97
TGN
Golgi apparatus
Cell migration
NF-κB
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12964-018-0230-5
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