Müller glia-mediated protection of retinal ganglion cells from ethambutol-induced neurotoxicity through brain-derived neurotrophic factor

Abstract Background Ethambutol (EMB)-associated optic neuropathy is the most common toxic optic neuropathy and poses a significant visual threat worldwide. This study aimed to investigate the neuroprotective roles of Müller glia, the most abundant macroglia in the retina, and their associated growth...

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Detalhes bibliográficos

Principais autores:	Hui-Chen Cheng, Yu-Hui Wong, An-Guor Wang, Shih-Wei Chen, Yong-Lin Yang, Hsien-Chia Juan, Roxanne Hsiang-Chi Liou, Jenn-Yah Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-11-01
coleção:	Cell Communication and Signaling
Assuntos:	Brain-derived neurotrophic factor Ethambutol Müller glia Optic neuropathy Retinal ganglion cell
Acesso em linha:	https://doi.org/10.1186/s12964-025-02478-4
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