Validated comprehensive RP HPLC approach for separation and quantification of solifenacin and mirabegron in the presence of their degradation products

Abstract A rapid and efficient High-Performance Liquid Chromatography (HPLC) method was developed and optimized for the separation and quantification of solifenacin succinate (SOL), mirabegron (MIR), solifenacin impurities A (SOL IMP A), I (SOL IMP I) and mirabegron metabolite (MIR MET) using a C18...

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Autori principali:	Ebraam B. Kamel, Mohamed Badrawy, Israa M. Nour
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2026-03-01
Serie:	Scientific Reports
Soggetti:	Mirabegron Solifenacin Impurities Metabolites HPLC Stability-indicating
Accesso online:	https://doi.org/10.1038/s41598-026-39569-2
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