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STING-driven activation of T cells: relevance for the adoptive cell therapy of cancer

Adoptive cell therapy (ACT) can successfully treat hema-topoietic cancers but lacks efficacy against solid tumors. This is due to insufficient T cell infiltration, high tumor heterogeneity, frequent antigen loss with subsequent tumor escape, and the immunosup-pressive tumor microenvironment (TME). A...

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Váldodahkkit: Fabian Richter, Christophe Paget, Lionel Apetoh
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Shared Science Publishers OG 2023-11-01
Ráidu:Cell Stress
Fáttát:
Liŋkkat:http://www.cell-stress.com/researcharticles/2023a-richter-cell-stress/
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