Histone dynamics mediate DNA unwrapping and sliding in nucleosomes
Nucleosomes tightly wrap ~147 DNA base pairs around an octamer of histone proteins, but how nucleosome structural dynamics affect genome functioning is not completely clear. Here authors employ all-atom molecular dynamics simulations of nucleosome core particles and observe that octamer dynamics and...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2021-04-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-021-22636-9 |
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