Efficacy and Safety of Bempedoic Acid in Patients With Hypercholesterolemia and Statin Intolerance

Background Inability to tolerate statins because of muscle symptoms contributes to uncontrolled cholesterol levels and insufficient cardiovascular risk reduction. Bempedoic acid, a prodrug that is activated by a hepatic enzyme not present in skeletal muscle, inhibits ATP‐citrate lyase, an enzyme ups...

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Autors principals:	Ulrich Laufs, Maciej Banach, G. B. John Mancini, Daniel Gaudet, LeAnne T. Bloedon, Lulu Ren Sterling, Stephanie Kelly, Erik S. G. Stroes
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2019-04-01
Col·lecció:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Matèries:	hypercholesterolemia lipids low‐density lipoprotein cholesterol muscle statin
Accés en línia:	https://www.ahajournals.org/doi/10.1161/JAHA.118.011662
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