Dissecting the Molecular Features of Systemic Light Chain (AL) Amyloidosis: Contributions from Proteomics

Amyloidoses are characterized by aggregation of proteins into highly ordered amyloid fibrils, which deposit in the extracellular space of tissues, leading to organ dysfunction. In AL (amyloid light chain) amyloidosis, the most common form in Western countries, the amyloidogenic precursor is a misfol...

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Bibliographic Details

Main Authors:	Paola Rognoni, Giulia Mazzini, Serena Caminito, Giovanni Palladini, Francesca Lavatelli
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2021-08-01
Series:	Medicina
Subjects:	amyloidosis immunoglobulin light chains protein misfolding amyloid fibrils post-translational modifications
Online Access:	https://www.mdpi.com/1648-9144/57/9/916
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