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Prevalence and Phenotype of Transthyretin Val122Ile Variant in the Hispanic Community Health Study/Study of Latinos

Background: Hereditary transthyretin amyloid cardiomyopathy is commonly caused by the Val122Ile variant, a mutation found in non-Hispanic individuals of West African descent but understudied among the Hispanic/Latino (H/L) population, despite their admixed genetic ancestry (African ancestry [AA], Eu...

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Principais autores: Priscilla Duran-Luciano, MD, Ambarish Pandey, MD, Katrina Swett, MS, Gregory A. Talavera, MD, MPH, Martha Daviglus, MD, PhD, MPH, Barry E. Hurwitz, PhD, Sanjiv J. Shah, MD, Tamar Sofer, PhD, Scott D. Solomon, MD, Susan Cheng, MD, MPH, Larissa Aviles-Santa, MD, MPH, Humberto Parada, Jr., PhD, Bharat Thyagarajan, MD, PhD, MPH, Franklyn Gonzalez, II, MS, Mayank M. Kansal, MD, James Tauras, MD, Mathew S. Maurer, MD, Carlos J. Rodriguez, MD, MPH
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-08-01
coleção:JACC: Advances
Assuntos:
amyloidosis
cardiomyopathies
cohort studies
epidemiology
Hispanic/Latino
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2772963X25004582
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