Bioinformatic Description of Immunotherapy Targets for Pediatric T-Cell Leukemia and the Impact of Normal Gene Sets Used for Comparison

Pediatric lymphoid leukemia has the highest cure rate of all pediatric malignancies, yet due to its prevalence, still accounts for the majority of childhood cancer deaths and requires long-term highly toxic therapy. The ability to target B-cell ALL with immunoglobulin-like binders, whether anti-CD...

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Detalhes bibliográficos

Principais autores:	Rimas J Orentas, Jessica eNordlund, Jianbin eHe, Sivasish eSindiri, Crystal eMackall, Terry J Fry, Javed eKhan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2014-06-01
coleção:	Frontiers in Oncology
Assuntos:	Immunotherapy Leukemia bioinformatics Adoptive immunotherapy Antibody therapy chimeric antigen receptors
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00134/full
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