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Quantitative global and gene-specific promoter methylation in relation to biological properties of neuroblastomas

<p>Abstract</p> <p>Background</p> <p>In this study we aimed to quantify tumor suppressor gene (TSG) promoter methylation densities levels in primary neuroblastoma tumors and cell lines. A subset of these TSGs is associated with a CpG island methylator phenotype (CIMP) in other tumor types.</p> <p>Me...

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Principais autores: Kiss Nimrod B, Kogner Per, Johnsen John, Martinsson Tommy, Larsson Catharina, Geli Janos
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2012-09-01
Serier:BMC Medical Genetics
Fag:
Neuroblastoma
Pyrosequencing
CIMP
BLU
CASP8
DCR2
CDH1
RASSF1A
RASSF2
Online adgang:http://www.biomedcentral.com/1471-2350/13/83
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