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Serum IL-27 levels increase in subjects with hypothyroidism and are negatively correlated with the occurrence of nonalcoholic fatty liver disease

BackgroundThe level of serum interleukin-27 (IL-27) was significantly decreased in the obesity group. After injection of IL-27, obese mice showed significant weight loss,reduced fat accumulation, improved insulin resistance and hepatic steatosis.IL-27 plays a key role in the regulation of metabolic...

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Principais autores: Yahui Wen, Heng Zhang, Ning Yang, Xia Gao, Zhe Chen, Jia Liu, Guang Wang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-08-01
coleção:Frontiers in Endocrinology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2023.1173826/full
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